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Various migraine medications including pills and injectables laid out next to a stethoscope.


Migraines can significantly impact daily life, and effective management often involves two main categories of migraine medications: abortive and preventive treatments.


Understanding the difference between these two types can help individuals find the right approach to manage their symptoms.


Abortive Medications

Abortive medications are designed to relieve migraine symptoms once an attack has started. They work quickly to alleviate pain and other symptoms, allowing individuals to return to their normal activities.

Examples of Abortive Medications:

  • Triptans: These are a popular choice, including sumatriptan and rizatriptan (Maxalt). They target serotonin receptors to reduce inflammation and constrict blood vessels.
  • NSAIDs: Nonsteroidal anti-inflammatory drugs like ibuprofen (Advil) and naproxen can help reduce pain and inflammation.

Preventive MedicationsMan experiencing severe headache, representing the need for effective migraine medications.

Preventive medications are taken regularly to reduce the frequency and severity of migraine attacks. They are not intended for immediate relief but rather to minimise the likelihood of future migraines.

Examples of Preventive Medications:

  • Tricyclic Antidepressants (TCAs): Amitriptyline is commonly prescribed for migraine prevention, helping to modulate pain perception.
  • Beta-Blockers: Medications like propranolol can help reduce the frequency of migraines by affecting blood flow and heart rate.
  • CGRP Inhibitors: Newer medications such as Ajovy and Emgality specifically target the calcitonin gene-related peptide involved in migraine attacks.

Conclusion

In summary, abortive medications provide quick relief during a migraine attack, while preventive medications help reduce the frequency and intensity of future episodes.

It’s essential to consult a healthcare provider to determine the best treatment plan tailored to individual needs.

Understanding these categories can empower migraine sufferers to manage their condition more effectively.


Written by:

Haeley Kan
Associate Headache Clinician